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Naprosyn 500 Mg Tablet

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300 Tablets $185.00

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Naprosyn 500mg contains 500 mg of naproxen — the standard twice-daily dose for osteoarthritis and rheumatoid arthritis. Ships from India. Delivery to the USA takes 7–14 days, 100% delivery guaranteed. Free shipping on orders over $100.

StrengthNaproxen 500 mg
Active IngredientNaproxen (NSAID)
Used ForOsteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain
How to TakeOne tablet twice a day with food
Pharmaceutical CompanyRPG Life Sciences Ltd
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  • Tracked worldwide shipping
  • Reship or refund if your parcel does not arrive

What is Naprosyn 500mg?

Naprosyn 500mg is a full-strength naproxen tablet made by RPG Life Sciences in India. Each tablet contains 500 mg of naproxen — the dose most often prescribed twice a day for osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Because each tablet is a full dose, it suits people who take naproxen regularly. For lighter or as-needed use, Naprosyn 250mg gives more flexibility.

How Naproxen Works

Naproxen is a non-selective NSAID: it blocks both COX-1 and COX-2, the enzymes that make prostaglandins. Lower prostaglandin levels mean less pain, swelling and fever.

Its main advantage is a long half-life — about 12 to 17 hours — so one dose lasts 8 to 12 hours, and two doses a day are enough for most conditions. Among traditional NSAIDs, naproxen at standard doses has one of the lower cardiovascular risk profiles; its main drawback is stomach irritation.

How to Take Naprosyn 500mg

  • Arthritis: one tablet twice a day, morning and evening, with food. The maximum is usually 1,000 mg a day; some people need 1,500 mg for a short period on a doctor’s advice.
  • Acute pain: one tablet to start, then 250 mg every 6–8 hours as needed.
  • Swallow whole with a full glass of water and food.
  • For arthritis, give it 1–2 weeks of regular use to judge the full effect.

Protecting Your Stomach on Daily Naproxen

Regular naproxen at 1,000 mg a day is effective but hard on the stomach lining. If you take it daily:

  • Always take it with a meal.
  • Ask your doctor about a stomach-protecting medicine (a proton pump inhibitor such as omeprazole), especially if you are over 65 or take aspirin, steroids or blood thinners.
  • Avoid alcohol, which adds to the risk of bleeding.
  • Report indigestion that does not go away, black stools or vomiting blood immediately.

Side Effects

Side effects are usually mild and settle when the medicine is stopped. Taking naproxen with food helps.

Common and usually mild:

  • Heartburn, indigestion or stomach pain
  • Nausea or constipation
  • Headache, dizziness or drowsiness
  • Ringing in the ears
  • Mild ankle swelling

Stop and get medical help right away if you have:

  • Black, tarry or bloody stools, or vomiting blood or material that looks like coffee grounds — signs of stomach bleeding.
  • Chest pain, shortness of breath, weakness on one side of the body or slurred speech — NSAIDs can raise the risk of heart attack and stroke.
  • Swelling of the face, lips or throat, wheezing, or a widespread rash — a possible allergic reaction.
  • Yellowing of the skin or eyes, or dark urine — possible liver problems.
  • Passing much less urine than usual, or swelling of the legs and ankles.

Who Should Not Take It

Do not use Naprosyn if you:

  • Are allergic to naproxen, or have had asthma, hives or a reaction after taking aspirin or any other NSAID.
  • Have an active stomach ulcer or bleeding in the stomach or bowel, or have had one in the past.
  • Have severe heart failure, or are about to have (or have just had) heart bypass surgery.
  • Have severe kidney or liver disease.
  • Are in the last three months of pregnancy.

Talk to a doctor first if you:

  • Have heart disease, high blood pressure or have had a stroke, or smoke.
  • Take a blood thinner (warfarin, apixaban, clopidogrel), low-dose aspirin, an SSRI antidepressant, steroids, lithium, methotrexate, or a blood-pressure medicine such as an ACE inhibitor, ARB or diuretic.
  • Are over 65, drink alcohol regularly, or have had stomach problems in the past.
  • Are pregnant, trying to get pregnant or breastfeeding.

Do not take two NSAIDs together — that includes over-the-counter ibuprofen, naproxen and aspirin. Use the lowest dose that controls your pain for the shortest time.

Please consult your doctor before using this medicine.

How to Store It

  • Store at room temperature, below 86°F (30°C), away from heat, moisture and direct sunlight.
  • Keep the tablets in their strip until you need one; do not keep them in the bathroom.
  • Keep out of reach of children and pets.
  • Do not use after the expiry date printed on the pack.

Shipping, Delivery and Discreet Packaging

  • Ships from: India
  • Delivery to the USA: 7–14 days, with a tracking number provided once your order ships
  • Shipping: free on orders over $100
  • Delivery guarantee: 100% delivery guaranteed — see our shipping policy
  • Discreet packaging: the outer box does not show the name Naprosyn 500mg or the drug name
  • Pack sizes: choose a pack above to see the current price

Sources and Medical Review

The medical information on this page is drawn from U.S. National Library of Medicine references, published prescribing information and independent evidence reviews.

Celecoxib, naproxen, diclofenac and indomethacin are prescription-only medicines in the USA. Naprosyn 500mg is manufactured in India and is not an FDA-approved product. The information on this page is for reference only and does not replace advice from a licensed doctor or pharmacist.

Frequently Asked Questions

What is Naprosyn 500mg used for?

Mainly osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, and also acute pain, tendinitis and bursitis.

How often should I take Naprosyn 500mg?

Usually twice a day, about 12 hours apart, with food.

Can I cut Naprosyn 500mg in half?

Plain naproxen tablets can usually be split, but a 250 mg tablet is a simpler way to get a lower dose.

Is naproxen safer for the heart than other NSAIDs?

Studies suggest naproxen at standard doses has one of the lower heart risks among traditional NSAIDs, but no NSAID is risk-free for people with heart disease.

How long can I take Naprosyn 500mg?

As long as your doctor advises, using the lowest effective dose and with regular checks of blood pressure and kidney function.

What should I avoid while taking Naprosyn?

Other NSAIDs (ibuprofen, aspirin for pain), heavy alcohol, and taking it on an empty stomach.