Nise Gel
05 Tube $60.00
Nise Gel by Dr. Reddy's combines nimesulide 1%, methyl salicylate 10%, menthol 5% and capsaicin for back, neck and muscle pain. Ships from India. Delivery to the USA takes 7–14 days, 100% delivery guaranteed. Free shipping on orders over $100.
| Strength | Nimesulide 1% + methyl salicylate 10% + menthol 5% + capsaicin 0.025% |
|---|---|
| Pack | 30 g tube |
| Used For | Back pain, stiff neck and shoulders, sprains, muscle aches |
| How to Use | Thin layer 3–4 times a day, up to 7 days |
| Pharmaceutical Company | Dr. Reddy's Laboratories Ltd |
- Discreet packaging on every order
- Tracked worldwide shipping
- Reship or refund if your parcel does not arrive
Category: Painkiller
On this page
What is Nise Gel?
Nise Gel is a combination pain-relief gel from Dr. Reddy’s Laboratories. Each gram contains nimesulide 1%, methyl salicylate 10%, menthol 5% and a small amount of capsaicin.
It is popular in India for back pain, stiff neck and shoulders, sprains and muscle aches. Nimesulide is not approved by the FDA, and nimesulide tablets are restricted in many countries because of liver risk; the gel delivers far smaller amounts into the body, but it should still be used for short periods only.
How the Four Ingredients Work
- Nimesulide — an NSAID that reduces inflammation in the tissue under the skin.
- Methyl salicylate — oil of wintergreen; a counter-irritant that warms the skin and eases aching.
- Menthol — a cooling counter-irritant that distracts from deeper pain.
- Capsaicin — from chili peppers; gives a gentle warming sensation and dulls pain signals over time.
How to Use Nise Gel
- Apply a thin layer to the painful area and massage gently until absorbed.
- Use 3 or 4 times a day, for no more than 7 days at a time.
- Expect a warm-then-cool sensation. That is normal; strong burning is not.
- Apply only to unbroken skin — never to cuts, grazes, eczema or infected skin.
- Keep it away from the eyes, mouth, nose and genitals. Wash your hands after applying, unless you are treating your hands.
- Do not cover the area with a tight bandage or use a heating pad over it.
- Do not use more than one pain-relief rub on the same area at the same time.
- Stop and see a doctor if the pain has not improved after 7 days, or gets worse.
Nise Gel vs Other Gels We Stock
| Gel | Main ingredient | Feels |
| Nise Gel | Nimesulide + methyl salicylate + menthol + capsaicin | Warm, then cool |
| Voveran Emulgel | Diclofenac 1% | Cool, non-greasy |
| Fastum Gel | Ketoprofen 2.5% | Cool |
| Counterpain | Methyl salicylate + menthol + eugenol | Hot |
Side Effects
Side effects are usually limited to the skin.
Common and usually mild:
- Warmth, tingling or redness where applied
- Mild itching or dryness
Stop and get medical help right away if you have:
- Blistering, peeling, severe burning or a spreading rash where you applied it.
- Swelling of the face, lips or throat, or difficulty breathing.
- Black stools, vomiting blood or stomach pain (rare with gels, but possible with heavy use).
Who Should Not Use It
Do not use Nise Gel if you:
- Are allergic to nimesulide, aspirin or salicylates, other NSAIDs, or chili/capsaicin.
- Take a blood thinner such as warfarin — methyl salicylate can be absorbed and increase bleeding risk.
- Are pregnant or breastfeeding, or under 12 years old.
- Have liver disease.
Talk to a doctor first if you:
- Have asthma triggered by aspirin.
- Take NSAID tablets or aspirin.
Please consult your doctor before using this medicine.
How to Store It
- Store at room temperature, below 86°F (30°C). Do not freeze.
- Close the cap tightly after each use.
- Keep out of reach of children — swallowing a medicated gel or balm can be harmful.
- Do not use after the expiry date printed on the tube.
Shipping, Delivery and Discreet Packaging
- Ships from: India
- Delivery to the USA: 7–14 days, with a tracking number provided once your order ships
- Shipping: free on orders over $100
- Delivery guarantee: 100% delivery guaranteed — see our shipping policy
- Discreet packaging: the outer box does not show the name Nise Gel or the drug name
- Pack sizes: choose a pack above to see the current price
Sources and Medical Review
The medical information on this page is drawn from U.S. National Library of Medicine references, published prescribing information and independent evidence reviews.
- Topical NSAIDs for acute musculoskeletal pain in adults — Cochrane review (PubMed)
- Salicylate-containing rubefacients for acute and chronic musculoskeletal pain — Cochrane review
Nimesulide is not approved by the FDA. Nise Gel is manufactured in India and is not an FDA-approved product. The information on this page is for reference only and does not replace advice from a licensed doctor or pharmacist.
Frequently Asked Questions
What is in Nise Gel?
Nimesulide 1%, methyl salicylate 10%, menthol 5% and a small amount of capsaicin.
What is Nise Gel used for?
Back pain, stiff neck and shoulders, sprains, strains and muscle aches.
Why does Nise Gel feel hot?
Methyl salicylate and capsaicin create warmth on the skin. Mild warmth is normal; stop if it becomes painful burning.
Is nimesulide safe?
Nimesulide tablets are restricted in many countries because of liver risk. The gel delivers much less into the body, but use it only for short periods and not if you have liver disease.
Can I use Nise Gel with a heating pad?
No. Heat increases absorption and can cause burns.
Can I use Nise Gel if I take warfarin?
No. Methyl salicylate can be absorbed through the skin and increase bleeding risk with blood thinners.
