Erectile Dysfunction Treatment
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What is an ED treatment drug? -Preliminary knowledge for improving ED
What is an ED treatment drug?
ED ( Erectile Dysfunction ) is a disease that many men suffer from.
ED refers to a condition in which sufficient erection cannot be obtained or maintained during sexual intercourse and satisfactory sexual intercourse cannot be achieved.
There is also a research report that as many as 11.3 million men are suffering from ED .
One in four men say that they can’t have sexual activity sometimes, if not always.
There is no need to give up saying “I can’t help it because I’m aging” or “I can’t help it because I have a lot of work stress”.
Currently, various ED treatments are on the market.
Not to mention those in their 30s and 40s who are in the prime of their work, but there are also many people in their 60s and 70s who think that they should have been treated earlier.
Let’s face ED with a little courage and realize a comfortable sexual life.
ED (Erectile Dysfunction) Symptoms
There are various people who suffer from ED, including elderly people, working salaried workers, overly stressful work, nervous and atrophied people, people with trauma, etc. Symptoms are also different.
If you have only one symptom of “erection does not last or can not be maintained” and you are living a satisfying sexual life after that, it is not necessarily ED.
The definition of ED = erectile dysfunction is “a condition in which an erectile dysfunction cannot be obtained even when given sexual arousal material, and the sexual life is unsatisfactory.” In other words, if the man himself is aware of this condition, he will be diagnosed with ED.
Erection is a physiological phenomenon triggered by sexual stimulation in healthy adults. The details of the erection mechanism will be described later, but to put it simply, an erection is caused by a large amount of blood flowing into the corpus cavernosum of the male genitalia.
There are various causes, but the important point is to “improve blood flow” in order to improve the dysfunction that causes poor blood flow and prevents erection.
Face the individual background and causes of ED, find a treatment that suits you, and take a step towards a trouble-free nightlife.
Main ED symptoms
Symptoms of ED vary from patient to patient.
“I get excited when I get sexual stimulation, but I can’t get an erection.” “It takes a long time to get an erection.” “I’m taking naturally-derived energetic agents such as maca and maca, but I can’t have sexual intercourse that I’m fully satisfied with,” and “I’m not confident in sexual activity.”
There are also free ED self-checks that do not require you to enter personal information on the Internet, so if you are interested, please try them.
The causes of ED vary from person to person.
Some people are stressed by work, aging, and tired, while others are caused by lifestyle-related diseases such as high blood pressure and diabetes.
ED caused by stress is called psychogenic ED.
In addition, ED caused by hypertension, dyslipidemia, arteriosclerosis left untreated, and poor blood circulation is called organic ED.
Drug-induced ED can also be caused by drugs that you are taking for other diseases.
The inability to obtain or maintain an erection with sexual stimulation and to have satisfactory intercourse with a partner is classified as one of the above EDs.
Detailed explanation of ED symptoms-Four types of erectile dysfunction -Psychogenic ED caused by social stress and complex, organic ED mainly caused by lifestyle, mixed ED that combines both inner and outer surfaces, Explains the four symptoms and causes of ED, such as drug-induced ED, which causes the onset of the drug you are taking.
mechanism of erection
When sexually stimulated, the brain sends signals through nerves.
Then, the blood vessels in the place called the corpus cavernosum of the penis expand and blood flows in.
Nitric oxide is released from the brain via nerves by sexual stimulation, and a vasodilator called cGMP (cyclic guanosine monophosphate) increases in the penis.
When sexual arousal subsides, such as after ejaculation, an enzyme called PDE5 (phosphodiesterase 5) reduces the amount of cGMP, reduces blood flow in the corpus cavernosum, and subsides the erection.
An enzyme called PDE5 has the role of degrading cGMP.
There are several types of PDE, and PDEs 1 to 11 called isozymes have been discovered, but PDE5 occupies the most important position for increasing blood flow to the corpus cavernosum penis.
It is an essential substance because the erectile state will continue for a long time without PDE5, which calms cGMP, which has a vasodilatory effect.
Healthy men have a good balance of cGMP and PDE5, which allows them to have normal erections upon sexual stimulation.
ED remedies focus on the function of PDE5 and have the role of helping the condition of impotence and erectile dysfunction due to stress and functional causes.
However, as long as it is a drug, there are some contraindications (prohibited conditions), so be sure to acquire the correct knowledge.
Why do erections occur? Mechanism of Erection Erection is one of the essential physiological phenomena for satisfying sexual intercourse. Knowing the mechanism, the index “EHS” that can diagnose whether your own erection hardness is normal, and knowing the size of other people’s erections will be useful for early detection and improvement of ED.
Types of ED drugs
There are many different types of ED medications that can help you maintain an erection .
By ingredient, there are four types: sildenafil, tadalafil, vardenafil, and avanafil.
In addition, drugs containing sildenafil include Viagra , which is often heard at medical institutions, and its generic Viagra.
Among them, generic Viagra also sells an OD type that can be taken without water in addition to regular tablets.
The advantage of the type that you can drink without water is that you can take it easily without anyone noticing .
Tadalafil is known as a prescription drug named Cialis .
Some active ingredients have generic drugs approved in USA, while others do not.
If you want to reduce drug costs, please consult your doctor or pharmacist.
Also, insurance may or may not be covered. Insurance may be available, such as ED caused by lifestyle-related diseases such as diabetes , but it is generally out of insurance.
The medicines we handle vary depending on the hospital or clinic, so please check with your medical institution in advance.
If you do not have time to visit a medical institution, you can purchase it online.
When obtaining ED drugs through personal import or mail order through personal import agency, it is important to collect safety information so that you can take them safely.
Learn more about ED (erectile dysfunction) drugs ED drugs, as the name suggests, are drugs that improve erectile dysfunction. It explains in detail the characteristics such as the effects and side effects of typical therapeutic drugs, the appropriate way to take them, what kind of symptoms people use, the effectiveness and safety, and the reasons why ED treatment is not covered by insurance.
Representative ED therapeutic drugs ~PDE5 inhibitors~
ED drugs are medicines called PDE5 inhibitors.
One of the enzymes that plays an important role in the mechanism of erection is PDE5 (phosphodiesterase 5).
When a healthy man receives sexual stimulation, a substance called cGMP (cyclic guanosine monophosphate) is produced from the brain through nerves, and the blood vessels in the penis expand and the blood flow to the corpus cavernosum increases, causing an erection.
Then, when sexual stimulation is released, PDE5 is secreted and the blood vessels in the corpus cavernosum constrict to reduce the blood flow to the penis. The penis then returns to normal.
In short, PDE5 plays a role in inhibiting the erectile state.
Conversely, inhibition of PDE5 increases penile blood flow and maintains an erection.
Viagra , which was launched as a pioneering drug for ED treatment, was originally developed as a drug for angina pectoris, but development was discontinued due to poor results as a drug for angina pectoris.
After the development was discontinued, there were many cases in which the male subject was reluctant to return the drug, and when asked why, it was found that it has a function to enhance male function, and the research was advanced.
As mentioned above, ED drugs are drugs that inhibit PDE5, so they do not act as stimulants in the brain.
It has the role of enhancing erection only when sexually stimulated.
Blood flow improvement effect
What does it mean to improve blood flow? Blood flow is the flow of blood through blood vessels.
It will be easier to understand if you imagine a rubber hose.
The image of the rubber hose being soft and thick and allowing water to flow easily is a state of good blood flow.
On the other hand, when the rubber hose shrinks and becomes thinner, making it difficult for water to flow, it means that the blood flow is poor.
When the blood vessels constrict due to stress or tension, it means that the blood flow is poor.
In the case of erectile dysfunction , it is difficult for blood to flow to the penis and normal erection is not possible. ED
due to poor circulation is common in people in their 40s and 50s who suffer from arteriosclerosis.
Arteriosclerosis is a condition in which blood vessels (rubber hose) become stiff and the inside becomes narrower, making it difficult for blood (water in the rubber hose) to pass through.
The muddy blood also interferes with blood flow, so people with lifestyle-related diseases are more likely to have ED.
In recent years, even young patients have been suffering from ED due to poor blood circulation caused by pressure on the penis while riding a racing bicycle.
If you improve your blood flow with the help of ED drugs, you may be able to solve your troubles.
Learn how to follow the precautions and use it safely.
The effects of ED drugs that maintain erections and their blood flow-enhancing effects that you should know about ED drugs that are effective for various penile problems are also called PDE5 inhibitors. It explains in an easy-to-understand manner the function of PDE5, which causes breakage, the causes that hinder the maintenance of an erection, and how to maximize the effect of erection medicine.
Mechanism of action
Before introducing the mechanism of action, I will first explain the mechanism of erection.
When a man receives sexual stimulation, nitric oxide is produced from the brain through nerves, reacts to nitric oxide, and cGMP is produced in the penis. cGMP is a substance that dilates blood vessels.
This cGMP causes blood to flow into the corpus cavernosum of the penis, resulting in an erection.
When sexual arousal subsides, such as ejaculation, the enzyme PDE5, which breaks down cGMP, is released to calm the erection.
Healthy men are well balanced, but ED sufferers lack cGMP.
As PDE5 continues to exist, PDE5 dominates and further degradation of cGMP leads to erectile dysfunction.
Therefore, by taking a drug that stops the action of PDE5, a so-called PDE5 inhibitor, the decomposition of cGMP is prevented.
When PDE5 is suppressed, blood vessels dilate, improving blood flow to the corpus cavernosum and maintaining an erectile state.
When sexual stimulation subsides due to ejaculation, blood vessels contract and quickly return to their original state.
In other words, it is a drug that does not work unless sexual stimulation enters the brain, so erections will not continue for a long time.
It is a mechanism that is triggered by stimulation and exerts its effect.
Ingredients for PDE5 inhibitors
There are four known active ingredients in ED drugs.
These are sildenafil, tadalafil, vardenafil, and avanafil.
Viagra is a well-known drug that contains sildenafil.
It is marketed by Pfizer, Inc., which is based in the United States.
A well-known ingredient containing tadalafil is “Cialis”.
This is sold by Eli Lilly and Company.
” Levitra ” is a well-known ingredient that contains vardenafil .
It is sold by Bayer, which is based in Germany.
In USA, these three ingredients are prescribed by medical institutions .
There are two types of generic drugs licensed in USA: Viagra and Cialis .
In addition to purchasing at the hospital, there is also a method of personal import.
You may also have heard of a drug called ” Stendra ” as a fourth ED treatment.
Although it is not a drug prescribed by medical institutions in USA, it contains the ingredient avanafil approved by the US FDA.
This is not officially approved in USA yet, so if you want to get it, you need to import it individually.
Detailed explanation of PDE5 inhibitors that are said to improve blood flow of ED therapeutic agents ED therapeutic agents are said to be PDE (phosphodiesterase) 5 inhibitors. Introducing the effects and mechanism of action, and four typical ingredients called PDE5 inhibitors that are effective in treating ED. Explains the main side effects and precautions of ingredients that improve blood flow.
History of ED drug development
In order to treat ED , it is common to take ED treatment drugs and ED improvement support supplements.
Here, we will explain about ethical drugs known as ED treatment drugs.
Just because you have ED doesn’t mean that everyone should take prescription drugs.
Since ED drugs have the function of promoting blood circulation, side effects such as facial hot flashes and headaches may occur.
Therefore, it is better not to take it if you have a disease or chronic disease that should not improve blood flow too much.
According to the package insert of Viagra , the contraindications (those who should never take it) are stated as follows.
Those who are taking nitrates or nitric oxide donors, those who are considered to have inappropriate sexual activity such as having cardiovascular disease, those who have severe liver dysfunction, and those who have a history of cerebral infarction / cerebral hemorrhage within 6 months Some people, such as some, have this kind of caution.
In the worst case, it may cause death or serious side effects, so make sure that you can take the medicine before using it.
Please be especially careful when using the Internet to procure overseas generic drugs without going to a medical institution.
Development history
How was Viagra , which was first used in the world as an ED drug , developed?
Viagra is the brand name of the drug, and the active ingredient (generic name) contained in the drug is called sildenafil.
In fact, sildenafil was being studied as an “angina drug”.
According to Viagra’s interview form, clinical trials in the United Kingdom did not show efficacy as an antianginal drug.
On the other hand, healthy adults who were the subjects of the initial clinical trial reported the development of penile erection.
In recent years, the mechanism by which sildenafil, which inhibits PDE5, relaxes corpus cavernosum smooth muscle and increases blood flow to induce penile erection has been clarified. started.
In January 1999, its efficacy and safety were recognized in USA, and it was approved as a drug with the indication of ” erectile dysfunction (patients who cannot maintain and maintain sufficient erection to perform satisfactory sexual activity)”. ..
In 2016, “Viagra OD Film” was launched as having exactly the same effect and safety as Viagra tablets.
This is a type that can be taken without water, and is expected to be useful for patients.
Unexpectedly Found Indications for Erectile Dysfunction-History of ED Treatments-Sildenafil, the active ingredient of the ED treatment Viagra, which everyone knows, was accidentally found in the treatment of angina. It explains the history of ED treatments, how the world’s first ED treatment was developed, and what kind of medicines appeared after that.
Indications
Indications for ED drugs are listed in the package insert of each formulation.
The indications for Viagra, Cialis , and Levitra are written as “erectile dysfunction (patients who are unable to achieve and maintain an erection sufficient for satisfactory sexual intercourse),” and all three drugs have the same indications.
A fourth ED drug, Stendra , which has not yet been approved in USA and is only available for personal import, has a similar description in the US package insert.
As stated in the package insert, this medicine can be taken if the patient himself feels that he is unable to perform satisfactory sexual intercourse due to erectile dysfunction. It’s an easy-to-try drug treatment, so don’t worry about it alone, let’s take action first.
However, please note that some people should not take ED treatments.
Details will be described later, but it should not be used for those who are taking drugs that should not be taken together with ED drugs (contraindicated drugs), or for those who have arrhythmia, severe liver damage, or cardiovascular disease as a chronic disease. is restricted.
This is because it may not be possible to use the medicine safely because the effect of the medicine may be more than necessary or the chronic disease may worsen.
If you are worried, please consult your doctor or pharmacist before taking.
For those with usage restrictions
According to Pfizer Pharmaceutical Co., Ltd., the manufacturer and distributor of the drug, the package insert of the drug includes such a description.
“Patients with a history of hypersensitivity to the ingredients of this drug” “Patients receiving nitrates or NO donors” “Patients with severe liver damage” “Patients with hypotension or management by treatment There are cases where it is clearly stated that it should not be used, such as “patients with high blood pressure who have not been treated”, “patients who are receiving amiodarone hydrochloride”, and “patients who are taking Riosiguato”.
If applicable, please do not take it at your own discretion by obtaining it from a personal import agency site.
Also, in the elderly, the metabolism is low, so the medicine stays in the body for a long time.
The same applies to patients with poor renal and hepatic functions, and because it is difficult for the drug to be excreted from the body, it will be affected by the drug for a longer period of time than necessary.
Depending on your condition, you may be able to take small doses at your doctor’s discretion, so follow your doctor’s instructions.
Patients at risk of priapism (multiple myeloma, leukemia, etc.) and patients with structural defects in the penis have a note in the section on height administration.
It’s not that you can’t take it, but you need to be careful for safe use.
Indications for ED drugs ~ Drugs that promote erectile function ~ ED drugs are suitable for most people with symptoms of erectile dysfunction. If you have sexual desire but do not get an erection, do not have an erection that is hard enough, do not have an erection that lasts, or are suffering from breakage, you will be able to get a strong erection with the correct dosage.
What is Viagra, an ED treatment drug?
Viagra is the world’s first erectile dysfunction improving drug manufactured by the leading pharmaceutical manufacturer Pfizer .
Pfizer is an American company that continues to be at the top of the pharmaceutical industry as a manufacturer of original products, conducting research in various fields for patients who are in trouble due to lack of treatment.
It has a good reputation for its effectiveness and safety.
Viagra contains sildenafil as an active ingredient. Since its sale, it has been loved by many people.
Patients who had concerns such as “I had given up with my partner”, “I had given up because of my age”, “I wanted a child but had difficulty in sexual activity”, and “I felt pressured because sexual activity was not fun”. In the past when there were many people, the appearance of Viagra changed history greatly.
After all, it has abundant experience in use, has accumulated evidence, and is recognized as a highly reliable drug.
The ease with which it should be taken one hour before sexual activity seems to have been a hot topic at the time.
This medicine works best when taken on an empty stomach, so avoid taking it on a full stomach or when you are drunk.
The medicine may not be effective.
The mechanism of action as a PDE5 inhibitor is explained in a separate section, so please check it.
Effects and features
Viagra is a PDE5 inhibitor released in 1998 by Pfizer, a major pharmaceutical company based in the United States, and is an ethical drug with a different mechanism from supplements and tonics.
At that time, it was developed as a treatment for angina pectoris, but during development it was discovered that it could improve erectile dysfunction, and clinical trials began as an ED treatment .
It attracted attention as the world’s first ED drug and continues to be used habitually to this day.
It is an ED treatment drug with the longest history, and it is a preparation with a sense of security that it is released by a highly reliable major pharmaceutical company .
Compared to other drugs, it seems to be a formulation that is relatively easily affected by food, but there are individual differences.
If you cannot take it on an empty stomach, you can take measures such as devising the meal content. You can get better results by taking measures that suit you, such as making a light meal and keeping the amount of food below the 8th minute of your stomach .
If you absolutely must eat, wait 30-40 minutes after taking the medicine and wait until the medicine is absorbed by your body before eating.
As for alcohol, it is not necessary to refrain from it because it can be expected to have a relaxing effect if it is a small amount.
As with other drugs, avoiding large amounts of alcohol is recommended.
Active ingredient sildenafil
This drug works by blocking PDE5 and increasing blood flow to the penis to promote and maintain an erection.
Viagra 25mg contains sildenafil 25mg as active ingredient and Viagra 50mg contains sildenafil 50mg as active ingredient.
Sildenafil was first marketed as an erectile dysfunction drug in the United States in 1998 and has been in the limelight as a dream drug. It has been used all over the world and data has been accumulated.
Patients taking nitroglycerin (nitrate ester) personally imported it at their own discretion, and as a result of taking it, there was a case of cardiac arrest, but it is currently described as “contraindication” and “contraindication for concomitant use”. , Such patients are prohibited from taking it.
Drugs containing sildenafil are also characterized by a variety of dosage forms.
There are also OD tablets that can be taken without water, OD film types, and generics approved in USA.
It takes 30 to 60 minutes for the effect to be obtained, and the duration is about 4 hours for 25 mg and 8 hours for 50 mg.
Since sildenafil has a vasodilating effect not only on the penis but also on various sites, it is being developed for diseases other than ED .
There are various types of sildenafil preparations, including Viagra, so it may be easier to find the one that suits you.
What is Viagra?-Effects, side effects, active ingredients, how to purchase online, etc.-Explain everything about Viagra, the world’s first approved ED treatment drug, effects, side effects, active ingredient sildenafil, dosage, generic drugs, mail order, etc. I’m explaining. Understand all about Viagra and improve erectile dysfunction.
What is ED drug Levitra?
Levitra is the second most developed erectile dysfunction improving drug in the world after Viagra.
It is marketed by Bayer Yakuhin in Germany, and its generic name is vardenafil.
Bayer Yakuhin is one of the world’s most famous pharmaceutical companies, and is constantly launching new drugs to meet unmet medical needs.
The mechanism of action is the same as Viagra , and by inhibiting an enzyme called PDE5 (phosphodiesterase 5), the blood flow to the penis is secured and an erection state is created.
It works only when sexually stimulated.
Although it was developed following Viagra, it is said to be less affected by food than Viagra.
If you eat a small amount of light food, you can feel the effect even after eating.
And the best feature is that the immediate effect is very high.
Compared to other PDE5 inhibitors, vardenafil is more soluble in water and is quickly absorbed by the body, which is the reason for its rapid efficacy.
How long does it take for the effect to appear, about 15 minutes after taking it .
Many people say, “Even if you forget to take your medicine, you can take it just before sexual intercourse, so you don’t have to worry about it.”
Effects and features
Levitra is a drug marketed by Bayer Pharmaceuticals, which is based in Germany.
In USA, it was the second to be sold after Viagra.
The feature is that it has an immediate effect compared to Viagra and Cialis .
Levitra takes effect in 15-30 minutes after taking it , while Viagra and Cialis take effect in 30-60 minutes.
If you want immediate results, Levitra is often chosen.
There are individual differences, but it is not completely unaffected by food.
It is positioned to be less affected by food than Viagra and more susceptible than Cialis.
Therefore, it is best to take it on an empty stomach, but it has a higher degree of freedom in taking time than Viagra .
Some patients say that a diet that keeps a light meal in the 8th minute of the stomach is effective, but there are individual differences, so let’s decide a guideline in consultation with your own body.
The reason for its high immediate effect is that the substance contained as an active ingredient is vardenafil, a component that dissolves more easily in water than other ED drugs .
It is recommended for those who feel that the effects of commercially available energy enhancers are slow. Basic side effects and precautions are the same as other ED treatment drugs.
Active ingredient vardenafil
Behind the progress of the development of vardenafil was the need to develop a drug that aims to increase the selectivity of PDE5 inhibition compared to the existing PDE5 inhibitors and to achieve a high effect.
Similar to Viagra, the mechanism of action is a mechanism that increases blood flow to the penis and obtains an erection by inhibiting PDE5.
As stated in the Levitra Tablets Drug Interview Form, it was launched in USA in 2004. Only 20 mg tablets have been on sale since 2007.
There are two standards for Levitra, 10 mg and 20 mg. It contains 10mg and 20mg of vardenafil as active ingredients, respectively.
Duration is 4 hours at 10mg and 8 hours at 20mg .
The usual dose is 10 mg of vardenafil, but if there are no side effects and no effect is obtained, the dose may be increased to 20 mg at the doctor’s discretion.
Patients aged 65 years or older and patients with liver disease may be prescribed starting from 5 mg once a day.
Such patients are restricted to a maximum dose of 10 mg.
The small tablets are easy to swallow and can be easily put in your wallet .
As with other ED drugs, many Levitra generics are manufactured and sold, so if you feel that other aphrodisiacs are slow to take effect, it may be worth trying.
What is ED drug Cialis?
Cialis is a product that has won the No. 1 market share in the erectile dysfunction drug market. The active ingredient in Cialis is Tadalafil.
Similar to Viagra and Levitra , it is an ED treatment drug that improves blood flow by inhibiting PDE5 and induces an erection .
A major feature of Cialis is its long duration. Due to the structure of the substance tadalafil, it is absorbed slowly in the body, so it has a mechanism that works for a long time.
There are individual differences, but the longest one lasts for about 36 hours .
Of course, it is a medicine that leads to an erection only when sexually stimulated, so it does not interfere with daily life. Please use with confidence.
However, it takes longer to start the effect than Viagra Levitra, so it is not suitable for those who want immediate effect.
Conversely, it can also be said that it is effective even if you drink it 2-3 hours before sexual activity.
Food affects 30 to 40 minutes after taking Cialis, so if 40 minutes or more have passed since taking Cialis, there is no problem eating.
If you drink it before the date, you can enjoy the day without worrying about anything after that.
This kind of convenience has made it popular, and it has become the No. 1 market share drug.
Effects and features
Cialis is an erectile dysfunction drug marketed by Eli Lilly in the United States.
It was launched in USA in 2007, and sales have been transferred from Eli Lilly to Nippon Shinyaku. Three standards are available: 5 mg, 10 mg and 20 mg.
It can be said that it is a medicine that allows you to decide the amount to take according to each individual while looking at the balance between the effects of erection and side effects.
Cialis has two characteristics. Compared to Viagra and Levitra, it has the longest duration of action of 36 hours and is not easily affected by meals, so it can be taken before meals.
It is a slow-acting and long-lasting drug, so it has the advantage of being able to be taken according to your lifestyle.
It is recommended to be taken 3 hours before sexual activity as it is slowly absorbed.
Viagra is recommended to be taken on an empty stomach 30 minutes before sexual activity, and Levitra is recommended to be taken on an empty stomach 15 to 30 minutes before sexual activity, but please note that only Cialis should be taken 3 hours before sexual activity.
As with other drugs, alcohol can be used in small amounts.
Cialis is marketed in more than 100 countries, and in 2013 it captured more than 40% of the ED treatment market share. It is no exaggeration to say that generic Cialis is sold by various pharmaceutical companies and is a highly reliable ED treatment drug that has accumulated experience in use around the world.
Active ingredient tadalafil
Cialis 5 mg contains tadalafil 5 mg as an active ingredient, Cialis 10 mg contains tadalafil 10 mg as an active ingredient, and Cialis 20 mg contains tadalafil 20 mg as an active ingredient.
It has the same mechanism of action as sildenafil.
One difference is that Tadalafil has a large block-like structure that is slowly absorbed by the body and boasts a long duration of 36 hours.
Tadalafil has other indications besides ED treatments.
There are three indications: pulmonary arterial hypertension, dysuria associated with benign prostatic hyperplasia, and ED treatments.
It is approved as a drug for pulmonary arterial hypertension under the name “Adcirca” and as a drug for dysuria associated with benign prostatic hyperplasia under the name “Zardia”.
The active ingredient contains the same tadalafil, but it should be noted that the method of administration and the medicines that should not be taken together differ depending on each disease.
It takes a long time for the medicine to disappear from the body, which may put a strain on the kidneys.
Patients with renal impairment may be instructed to limit the dose to 5mg at a time, or to wait 48 hours after taking 10mg.
What is ED drug Stendra?
Stendra is called the “fourth ED treatment” after Viagra Levitra Cialis . It is an ingredient developed by VIVUS in the United States and contains an active ingredient called avanafil.
In USA, it is not approved as an ethical drug by the Ministry of Health, Labor and Welfare, so it cannot be obtained from hospitals or clinics.
If you want it, you will have to buy it online from an import agent site for overseas products.
Therefore , it may be a little hurdle for those who have never been treated for ED to use it for the first time at their own discretion.
The package insert published in the United States contains a lot of medicines that you should be careful about when using them together, so you need to acquire solid knowledge.
Stendra is characterized by its high immediate effect and rapid disappearance from the body.
If it is early, the effect will start to appear in 15 minutes after drinking.
It lasts 3 to 6 hours, and some products are said to be less susceptible to the effects of food, so it is an ED treatment that is easy to take according to each person’s lifestyle .
No side effect reports have been published in USA, so if you experience any unusual symptoms such as headaches, as with other ED treatments, please consult a medical institution.
Effects and features
Stendra has emerged as the fourth ED treatment not yet approved in USA.
It is a drug developed by Vivus of the United States and contains avanafil as an active ingredient.
In USA, medicines that cannot be prescribed by medical institutions will be imported by individuals.
Like Viagra , Cialis and Levitra , it is a drug that inhibits PDE5 to increase blood flow and lead to an erection.
It is a drug that begins to take effect 15 minutes at the earliest, and usually 30 minutes after taking it, and is characterized by its immediate effect.
The duration is 3-6 hours.
It works quickly, is metabolized quickly, and disappears from the body, so depending on your lifestyle, it may fit you perfectly.
It is said that it is not easily affected by food and has relatively few side effects, but it is not clearly compared with the three preceding drugs.
Side effects such as headaches, stuffy nose, and hot flashes have been reported in the same way.
The most contraindicated medicines (drugs that should not be taken together) are listed, so please be careful when taking them. The probability of side effects such as hot flashes, headaches and priapism is not digitized in USA.
Stendra generics are being manufactured little by little because expectations are high as an ED treatment drug following Cialis, but please be careful of troubles with import agents when obtaining them.
Active ingredient Avanafil
Avanafil, an ingredient that was originally developed by a major USA pharmaceutical manufacturer, was entrusted to Vivus in 2001 with manufacturing and marketing rights around the world except for parts of USA and the Asian region.
2012, approved and marketed in the USA.
In the United States, it was sold under the brand name “SPADERA”. Some patients are particular about the safety of ingredients developed in USA.
Avanafil content is available in three types: 50mg, 100mg and 200mg.
Take from 100mg, determine the physical disparity of each individual, the occurrence of side effects, and whether or not it is effective, and adjust the way of taking the medicine between 50mg and 200mg.
One way is to buy 200mg, divide it in two with a tablet cutter sold at a pharmacy, and start with 100mg .
You don’t have to buy the same drug over and over again.
Its main feature is its immediate effect, but depending on the product containing Avanafil, it may be written that “you don’t have to take it on an empty stomach.”
However, the effect is affected by individual differences and dietary content, so if you want to achieve the best performance, it is recommended to take it on an empty stomach like other ED treatments.
New drugs and generic drugs for ED treatment
In the case of Viagra , many medical institutions charge 1,000 to 1,300 yen for 25 mg and 1,500 to 2,000 yen for 50 mg.
Viagra generic is sold for about 1,000 yen for 50 mg, so it is calculated to be about 500 yen cheaper per tablet.
If you take Viagra 50mg once a week, you will save 500 yen/day x 4 doses (for 4 weeks) = 2,000 yen/month.
Ask your healthcare provider how much you can save.
If you change to a cheaper generic drug , it is easy on your wallet, but many people say that safety is a concern.
There is no such thing as “no side effects because it is a new drug, side effects because it is a generic drug”.
Both new drugs and generic drugs are approved by the government if they are used in the same way, and they are effective and safe to use.
One difference is that the new drug has been developed over many years and has been clinically tested in humans many times, and it has a lot of experience in use since it was launched. Both generic drugs and generic drugs have cleared the USA approval standards, which are strict worldwide, so they can be used with peace of mind.
What is a new drug (original drug)?
Drugs are roughly divided into two types: “prescription drugs” that are prescribed at hospitals and “over-the-counter drugs” that can be purchased at drug stores.
Furthermore, ethical drugs can be divided into two categories: “new drugs (original drugs)” and “generic drugs (generic drugs)”.
New drugs are also called original drugs or pikashin.
Developing a new drug requires a long development period, a huge amount of labor, and funds.
We humans have fought against various diseases thanks to advances in medical care.
Even today, there are many diseases for which the development of medicines is desired, such as intractable diseases with a small number of patients, which are called rare diseases, and diseases that cannot be fundamentally treated and can only be treated symptomatically.
It takes decades to develop such medicines.
It will be delivered to patients only after finding effective substances, clearing in vitro experiments, animal experiments, drug stability tests, clinical trials in humans, etc., and recognizing efficacy and safety. increase.
New drug manufacturers who have obtained a patent for a new drug can exclusively manufacture and sell the drug for 10 to 20 years.
At the end of this period, the active ingredient of the drug will be approved for manufacture and sale by any pharmaceutical company and will be sold as a drug called a generic drug.
What are generic drugs?
Generic drugs are also called generic drugs.
A drug that contains exactly the same amount of the active ingredient as the new drug .
The difference is the taste, shape, color, additives, etc. of the medicine.
Additives may give you a negative image, but additives are also used in new drugs.
Unlike food additives, drug additives are used to prevent each drug from cracking or deteriorating and to maintain stability.
Although it contains the same ingredients in the same amount, it is also devised to add an easy-to-drink flavor and change it into an easy-to-drink form.
We are conducting various tests to prove that efficacy and safety are the same as new drugs and to be recognized by the government.
Compared to new drugs, the time required for research and development is shorter, about 3 to 5 years.
Since the development labor and cost are low, it can be delivered to patients at a lower price than the new drug while containing the same active ingredients as the new drug.
Not all medicines you receive from medical institutions have generic drugs, but if you want to reduce drug costs, please consult your doctor or pharmacist.
In USA, there is a growing movement to promote the spread of generic drugs in order to curb the ever-increasing medical costs.
Shape and dosage form of ED drug
There are two types of ED treatments : tablet type, OD tablet, and OD film type.
The tablet type is commonly taken with water.
Viagra is blue, Levitra is orange, and Cialis is yellow.
OD tablets are orally disintegrating tablets, which are a type of medicine that dissolves in the mouth without water.
Viagra comes in three dosage forms: tablets, OD tablets and OD film.
Like the OD tablet, the OD film is a film that melts in your mouth.
Compared to pills, it is much thinner, so it is easy to put in a wallet .
If you are an OD type, you can take it quickly at any time without noticing that you are taking the medicine.
Many patients suffering from ED are busy with work, and often desire an OD type that is easy to drink.
When taking OD type, there is one difference from tablets.
When you take it out of the individual packaging, do not leave it as it is and take it immediately.
OD tablets and OD films should not be stored in a state where they are exposed to air because they are less stable than tablets because they dissolve more quickly.
Viagra Tablets, Viagra OD Tablets, and Viagra OD Film are all released by Pfizer in the United States, so there is a sense of security that they are products of a major long-established pharmaceutical manufacturer.
Shapes and dosage forms of ED therapeutic drugs There are various dosage forms of ED therapeutic drugs, and the shapes and forms of the three major ED therapeutic drugs are tablets, oral tablets (troches), orally disintegrating tablets (chewable), effervescent tablets, and penetrating the body. It explains the types and characteristics of OD films and oral jelly that are easy to use and have immediate effects.
How to take ED treatment
It is important to follow the dosage and administration of medicines properly, and the same is true for ED medicines .
Viagra was called “dream medicine” and “blue diamond” when it was first released, and many people abused it without observing the dosage. Deaths due to drinking have also been reported.
If you take it correctly, there is no problem, so please adhere to the dosage.
The dosage varies depending on the medicine, for example, Viagra is 1 tablet of 25 mg or 50 mg once, and Levitra is 1 tablet of 10 mg or 20 mg.
For all PDE5 (phosphodiesterase 5) inhibitors, it is not desirable to take grapefruit juice with it and should be avoided.
This is because the component called furanocoumarin acid contained in grapefruit juice antagonizes the metabolic pathway of the drug, which may have an adverse effect on the body.
Also, if you use a small amount of alcohol, you can get a relaxing effect, so keep it in an appropriate amount.
The time it takes for the effect to appear varies depending on the ED treatment drug, so check how many minutes before sexual activity you should take it.
timing of taking
Briefly summarize the four methods of use.
Viagra should be taken on an empty stomach 30 minutes before sexual activity.
The longest duration is about 6 hours. Take on an empty stomach as it is easily affected by food.
Levitra should be taken 15 to 30 minutes before sexual activity. The duration is about 4 hours for the shorter one and about 8 hours for the longer one, but there are individual differences.
It is not easily affected by food, but if you eat until you are full or if you eat a meal with a lot of fat, absorption may be delayed and the effect may be delayed.
Cialis should be taken 1-2 hours before sexual activity.
For those who are required to develop the effect quickly, it is effective to take it on an empty stomach, and the duration is as long as 24-36 hours.
Although it is said that it is not easily affected by food, some doctors say that it is best to take it on an empty stomach in order to achieve a reliable effect and a quick onset of effect, so it can be said that it can be adjusted according to one’s physical condition and the situation of the day.
Stendra should be taken 15 to 30 minutes before sexual activity.
The duration is said to be 3 to 6 hours.
Since there is no instruction to take it on an empty stomach, it is positioned as a medicine that is not easily affected by food like Cialis.
As with all ED medications, keep alcohol to a minimum and do not drink until you are drunk.
Dosing interval
It is generally recommended to wait at least 24 hours before taking the next dose of ED drugs .
Taking this medicine at short intervals may cause side effects such as headache, facial hot flashes, and tachycardia.
If your doctor has prescribed Viagra 25mg, take it at 9pm on Saturday night and don’t take it until 9am the next Sunday, whether it works or not.
How to take the medicine is important to get the effect of the ED medicine correctly How to take the medicine is important to get the erection effect of the ED medicine. Check the 5 correct ways to take ED medicine and be sure to follow the dosing interval until the next dose. Taking the correct dose of ED medications can help you maintain a satisfying erection.
Side effects, contraindications, and precautions for ED drugs
Side effects of ED medications include hot flashes, dizziness, and headaches.
These symptoms may occur because dilating blood vessels improves blood flow.
According to the Viagra package insert, the incidence of headaches in clinical trials is about 10%.
About 10% of vasodilation such as hot flashes has been confirmed.
Other side effects include nasal congestion in some people due to increased blood flow, and tachycardia in others due to stress on the heart that pumps out more blood than normal.
Most are transient and the symptoms subside when the drug disappears from the body.
If you have a severe headache, you can treat it with a general headache medicine, so please consult your doctor or pharmacist.
In addition, side effects may be more likely to occur depending on your physical constitution, dietary content of the day, and physical condition.
In that case, it is effective to reduce the amount of the medicine you are taking, or to take the medicine that you normally take on an empty stomach 30 minutes after eating.
Since absorption is good on an empty stomach, the drug is absorbed a little more slowly when taken after meals.
Side effects may be avoided by changing the type of erection drug, changing the dose, and devising the way of taking.
side effects
Generally, the duration of ED treatment is said to be 4 hours.
It cannot be said unconditionally depending on the ingredients of each drug, but it takes 3 to 6 hours even if individual differences are taken into consideration.
As mentioned above, ED drugs do not act as stimulants, but rather as drugs that increase blood flow to the penis only when sexually stimulated, rather than drugs that promote sexual arousal.
Therefore, it is abnormal if the erection persists for more than a day.
If you experience this symptom, see a urologist as soon as possible.
The condition in which this erection continues too long is called preapism.
Venous priapism, in which the return of blood sent to the corpus cavernosum is poor and the circulation of blood deteriorates, resulting in tissue necrosis, and venous priapism, in which arteries in the corpus cavernosum are ruptured and new blood continues to flow into the penis. I have priapism arteriosus.
Especially in the case of venous erection persistence, there is data that half of them will have erectile dysfunction after the onset, and emergency treatment is required, so please consult a medical institution as soon as possible.
If a hard erection is painful, it is a symptom of suspected venous priapism.
On the other hand, if you have a soft erection and it is not painful, it is probably arterial priapism and the urgency is low, but it is recommended that you consult your doctor or pharmacist.
Side effects that you should know before taking ED drugs Although ED drugs are effective, they may also have side effects. It is important to know the main side effects such as headaches, hot flashes, and stuffy nose, as well as the causes and countermeasures of priapism, which rarely occurs when an erection does not subside, before taking erection pills.
Precautions for use
Many precautions are set not only for ED therapeutic drugs but also for various drugs.
It is very important to know the points to be aware of in order to use it safely because you are going to start treatment for ED .
As a common precaution for ED therapeutic drugs called DE5 inhibitors, taking is prohibited for those who are taking nitrates.
Contraindications for concomitant use will be described in detail later, so please check.
Those who have a history of cardiovascular disease or cerebral infarction, those who have renal or hepatic dysfunction, or who are taking medicine for athlete’s foot should not take ED drugs unless their safety cannot be guaranteed by a doctor’s judgment. there is.
Alcohol has a relaxing effect, so there is no problem in drinking a small amount of alcohol, but if you drink a lot, you will not be able to get the effect, so please refrain from drinking.
Dietary precautions include avoiding citrus fruit and fruit such as grapefruit juice.
Beware of chuhai and cocktails that contain grapefruit juice.
Furanocoumaric acid contained in grapefruit inhibits the metabolism of medicines, and side effects of medicines may become stronger, causing headaches and hot flashes.
There are various ways to obtain medicines, but if you use the medicine mail order at your own discretion, be sure to understand the precautions and protect yourself.
Handling precautions such as storage
Different medicines have different storage conditions.
If you do not store it properly, it will not be effective, and in some cases, side effects may occur.
Be sure to follow the storage method and expiration date described in the instructions attached to the medicine.
Deterioration of the contents may pose a health hazard.
The expiry date is often written on the back of the sheet containing the medicine (PTP sheet), but if you do not know it, we recommend that you contact a medical institution.
For example, PDE5 inhibitors such as Viagra and Cialis are indicated to be stored at room temperature (1-30°C).
There are also some that are listed as storing away from direct sunlight.
Also, if you are taking half a tablet after cutting it with a pill cutter, take the other half as soon as possible.
Avoid high temperature and humidity and store in a place not exposed to direct sunlight.
Avoid leaving pills in your pocket.
Please pay attention to the dosing interval as many medicines require that you wait 24 hours before taking the next dose.
Some of the types of medicines that are injected into the urethra, which will be described later, require storage in the refrigerator (2 to 8 ° C).
Follow the storage method of each drug and take it.
Precautions for ED therapeutic drugs Before taking ED therapeutic drugs, check in advance the precautions that must be taken before taking ED drugs, concomitant drugs that can be taken if the precautions are strictly observed, and contraindicated drugs that should not be used together. A remedy is not an aphrodisiac. Take it safely and effectively.
Contraindications for co-administration
There is a “package insert” for the medicine as an instruction manual for use.
Of course, it is attached to the ED treatment drug, and you can check it on the Internet.
There is an item in the package insert that says “Contraindications for combined use”.
“Contraindications for concomitant use” are medicines and foods that are “[absolutely] must not be taken (or eaten) with the medicine”.
Although it is listed in the “Contraindications” section at the beginning of the package insert, it is also written as “Refer to the Interactions section” and double-written in the “Interactions” section.
The more you write, the more you need to be careful.
This is because the pharmaceutical company that developed the drug anticipates the risks when conducting clinical trials, decides contraindicated drugs for concomitant use, and the Ministry of Health, Labor and Welfare recognizes those risks.
In addition to the contraindications for co-administration, there is also an item called “Precautions for co-administration”, but this is not a strict item that “[absolutely] should not be taken together.”
However, they should be used with caution, and may be used only after careful consideration by medical professionals, depending on the patient’s condition and in situations where the absence of these drugs could be life-threatening.
It is important to keep up-to-date with the latest information as there are cases where the precautions for co-administration are changed to contraindications for co-administration several years after the drug is released.
Contraindicated drugs
According to the Cialis package insert, nitric oxide and nitric oxide donors (nitroglycerin, amyl nitrite, isosorbide dinitrate) and the sGC stimulant riociguat (adempas) are contraindicated.
Nitrate and nitric oxide donors should never be taken together as they enhance the antihypertensive effect and may cause dizziness and light-headedness.
Viagra’s package insert lists amiodarone hydrochloride (ancaron tablet) in addition to the drugs written for Cialis.
The QTc prolongation effect of amiodarone hydrochloride, that is, arrhythmia, can cause stress on the heart.
There are pitfalls like this if you focus only on the improving effect of ED.
Levitra ‘s package insert states that in addition to the drugs listed for Cialis, drugs that inhibit CYP3A4 are contraindicated.
Simply put, it is a drug that interferes with the action of important enzymes that metabolize drugs and excrete them from the body.
Contraindications for itraconazole, which is a dangerous and familiar drug for athlete’s foot, are also applicable to antiarrhythmic drugs, etc.
If you have any illness and are taking medication, please consult your healthcare provider before taking any ED medication.
Contraindications for concomitant use of ED treatments-Viagra Levitra Cialis- There are various types of ED treatments, including the shapes and tablets of the three major ED treatments, oral tablets (troches), orally disintegrating tablets (chewable), Explains the types and characteristics of effervescent tablets, OD films that easily penetrate the body and have immediate effects, and oral jelly.
“Frequently Asked Questions” about ED treatments
Here are some frequently asked questions about taking ED drugs .
The first is the alleviation of headache symptoms, which are sometimes reported as side effects.
It is not uncommon for headaches to occur when taking ED medications dilates not only the penis but also the cerebral blood vessels.
In this case, take an anti-inflammatory analgesic such as loxoprofen (general pain reliever).
It is said that the possibility of adverse effects from concomitant use is low, so there is no problem if you take only one tablet if you feel pain.
If you have other diseases and are taking other medicines, take this medicine as directed by your doctor.
If you have a weak stomach, it would be better to have a stomach medicine prescribed together.
Next, I would like to talk about the effects of alcohol. The bottom line is that you can still drink alcohol while taking ED medications, but the important point is the amount.
If you drink a little, you can get a relaxing effect, so you can expect a synergistic effect with ED treatment drugs.
Please note that if you take too much, the medicine will not be effective.
Finally, there is the effect on the fetus.
There is also a report that the percentage of the active ingredient of the drug that transfers to the sperm is extremely low, and no abnormalities were found in animal experiments.
There are products that publish data and products that do not, so if you are concerned, please ask a medical institution.
Simple questions about ED medicinesIs it okay to use ED medicines every day?Is it okay to take headache medicine that suppresses side effects?Is it okay to drink and take it?Is it effective for fertility? I have summarized simple questions that are difficult for others to ask, such as what is the impact
Other ED treatments
In addition to PDE5 (phosphodiesterase 5) inhibitors such as Viagra , Cialis , Levitra , and Stendra , there are drugs used as ED treatment drugs .
Udenafil, a fifth PDE5 inhibitor, is one of them. Since it was developed in South Korea, it is expected to be the most suitable PDE5 inhibitor for Asians.
Currently, it is not licensed in USA and is only available online.
In addition, there are many options that can be a light of hope for men who cannot take PDE5 inhibitors due to chronic illness.
There are various products on the market, such as drugs that are injected directly into the urethra, supplements that are applied directly to the penis, and oral drugs that work on the sympathetic nervous system to increase blood flow by blocking α-receptors.
Even people who share the common problem of erectile dysfunction have different requirements for medicines.
There are various needs, such as whether safety is the first priority, whether immediate effect is desired, whether long duration is desired, whether cheapness is desired, or whether there is resistance to ingesting oral medicine into the body. should.
Unlike in the past, today we are in an era where we can meet various needs and obtain various types of medicines.
Let’s try it with the right knowledge first so that we can move forward one step instead of just worrying about it.
How to get an erection in addition to ED drugs
I considered taking an ED drug , but “I couldn’t take it because I had a chronic illness” “I gave up taking it because I was so hot” “I’m afraid to take prescription drugs” “I don’t want to go to the hospital, but I’m an individual In fact, many people say that importing is also a high hurdle.
For such people, it is recommended to start with aphrodisiacs and ED supplements.
There are many different supplements on the market, so find one that works for you.
There is a product lineup that can meet individual needs, such as products that use ingredients that have been used for a long time, such as supplements of naturally derived ingredients, and supplements that are applied directly to the penis instead of being drunk.
When purchasing overseas products, please carefully check the ingredients contained in each supplement and follow the usage instructions.
Some products labeled as energetic agents indirectly sell “nutrition tonics” and “fatigue recovery agents” as energetic agents.
If you are currently in the hospital, tell your doctor that you are using supplements to protect your health.
It takes a long time for the effect to appear compared to pharmaceutical products, so it is recommended that you check the label before purchasing.
Effect Efficacy
I would like to introduce you to a supplement that can be used as an energy booster.
Please be aware that the mechanism of action is completely different from that of the ED treatment drugs already introduced.
Sex enhancer supplements also contain a variety of active ingredients.
Among them, there are also supplements sold as energy boosters that contain only ingredients that promote recovery from fatigue, such as vitamins, maca, soft-shelled turtle extract, and garlic extract.
It does not have a direct mechanism of action such as increasing the blood flow to the penis and promoting an erection like a prescription drug.
There are many things that indirectly play a role in assisting erection.
Prescription drugs are the same, but you need to be careful because there are considerable individual differences in the effect.
Supplements containing ingredients such as arginine, zinc, and citrulline have been reported to promote blood circulation.
If it is an ED supplement that suits your lifestyle and physical condition, for those who want to treat ED with 100% naturally derived foods instead of prescription drugs, those who are restricted from taking prescription drugs, etc. Supplements may also be effective.
Also, if you are considering purchasing overseas imported products, it is important to collect sufficient information such as what kind of environment it is manufactured in, what kind of ingredients it contains, and whether there are any health hazard reports. is.
main ingredient
What kind of ingredients are contained in energetic agents (supplements)?
Although it may be listed as ED generic on the mail order, it is not a generic drug .
Ingredients that you have heard once, such as pit viper, scorpion, soft-shelled turtle, garlic, maca, ginseng, and zinc.
Mamushi is also a Chinese herbal medicine called anti-nasal in China, and has blood circulation promoting and nourishing tonic effects.
The ingredients contained in the pit viper are taurine, tyrosine, glutamic acid, etc.
Scorpion contains amino acids.
Although it does not contain any other special ingredients, there is a theory that since ancient times, it has had an image of increasing energy due to its strong poison.
Maca is originally a Peruvian vegetable.
Rich in minerals, it is said to be good for nourishment and tonic, and has a long history of being used by Peruvian men.
Zinc is a mineral necessary for the production of sex hormones, and foods containing more than the specified amount of zinc can be sold as food with nutrient function claims.
Supplement options are also available for those who want to treat ED with natural foods and those who have restrictions on the use of prescription drugs.
Strictly observe the dosage and administration, and consult a medical institution if you feel any abnormalities.
What is the difference between ED treatment drugs and energy enhancers/supplements What is the difference between ED treatment drugs and energy enhancers/supplements ? It is important to understand the erection-promoting effects of aphrodisiacs and supplements, the main ingredients, their effects, and their mechanisms of action, and to find a method for improving erectile dysfunction that suits you.
Difference from ED treatment
If you study hard to improve your troubles such as not getting an erection or having a broken heart, you will come across a wide variety of products and foods.
I’m sure some of you are wondering what kinds of drugs are available.
I will explain the difference between the words “ED cure”, “erectile drug”, and “energy stimulant” that are often heard.
“ED drug” is a drug that increases blood flow to the genital area and promotes an erection .
“Erection medicine” is also a term used synonymously with “ED treatment medicine”.
Viagra , Cialis , Levitra, etc. are known, but generic drugs that are cheap and easy to try, and imported products whose dose can be adjusted individually are applicable.
On the other hand, the term “energetic agent” is used in a broad sense.
It is a common name for medicines and general foods used to enhance sexual function, and is classified into medicines and others (foods, etc.).
In addition to the drugs mentioned above, there are also drugs that suppress or promote the secretion of sex hormones, as well as nutritional tonics and anti-fatigue drugs that claim to have an indirect sexual enhancement effect.
A hormonal agent called testosterone, foods such as soft-shelled turtle, maca, and garlic, and the above-mentioned ED remedy, all of which are collectively called “energetic agent”.
Find a treatment that suits you and lead a comfortable sex life.
Comparison of ED treatment drugs, aphrodisiacs, and erection supplements Do you know the difference between ED treatment drugs, aphrodisiacs, and erection supplements? Each of these has different definitions, uses, and effects, and it is possible to choose according to the purpose, such as ED treatment for fundamental treatment, aphrodisiac for sexual enhancement, and supplement for constitution improvement.
Choice of ED treatment
So far, I have touched on various ED treatments .
Each has its own characteristics, and there are various types such as those with excellent immediate effect, those that work slowly and have a long lasting effect, those that are not easily affected by food, those that can be drunk without water, those that are original products, and those that are generic products.
The medicines prescribed vary depending on the prescription of renal function, liver dysfunction and other chronic diseases such as high blood pressure.
Depending on the patient’s physique and preferred diet, the dose may be increased or decreased, and for patients with severe side effects, the dose should be reduced or the timing of administration should be adjusted, such as after meals. There is also
ED treatment drugs are generally free medical care, so it is possible to negotiate monthly drug costs by consulting with medical institutions and changing to generic drugs .
Since you are determined to treat and take the first step toward a comfortable sexual life, find the medicine that suits you best, know the dose and timing of taking the medicine that suits you, and treat ED safely and effectively. Let’s go.
If you have any concerns, we recommend that you consult a medical institution.
Currently, there are clinics with only male staff and clinics that are open late at night, so we are creating an environment where people can consult without being shy.
Introduction of ED treatments Several treatments have been developed for ED. Learn about the types and effects of PDE5 inhibitors that restore hardness to erections, the three major ED treatments and the fourth erectile dysfunction, and the domestic and international prescriptions of these generic drugs, and find the ED treatment that suits you.
How to get ED treatment
What are some ways to get ED drugs ?
There are two main methods.
The first is to get a prescription at a medical institution such as a hospital or clinic.
Basically, ED treatment is not covered by insurance, so you will receive medicine by “in-hospital prescription” where you will receive medicine at the clinic.
Prices vary depending on the clinic, so we recommend that you check the required amount in advance before visiting.
For medical treatment not covered by insurance, presentation of insurance card is not required.
There are many clinics that have a reception that considers privacy.
The second method is to purchase from an import agency site of overseas products by mail order.
Recommended for those who are busy and do not have time to go to the clinic, or for those who have already received ED medicine at the clinic but want only the usual medicine easily.
It is not a prescription from a medical institution, but you will be using it at your own risk, so it is important to fully understand the characteristics, side effects, and usage of the drug before ordering.
Even if it is inconvenient for you to have your parcel delivered to your home, you can protect your privacy by using convenience store pick-up.
When purchasing online, please pay close attention to counterfeit and imitation products so that there are no problems with payment.
Hospitals/specialty clinics
One way to obtain drugs for treatment is to have them prescribed by a medical institution.
In this case, the consultation fee and medicine price setting may differ depending on the medical institution.
It is a good idea to check in advance on the Internet or by phone.
Depending on the cause of ED , you may be covered by insurance.
In this case, you will need your insurance card, so be sure to bring it with you.
In general, most clinics that provide ED treatment are prescribed free medical treatment (self-financed medical treatment) instead of insurance medical treatment.
In this case, you do not need to submit your health insurance card, and your personal information will be protected.
In addition, some patients in their 40s and 50s, who are in their prime, suffer from lifestyle-related diseases such as hypertension and diabetes, while others in their 60s and 70s have experienced myocardial infarction, arrhythmia, and cerebral infarction. Some people do.
Being able to discuss your condition with a doctor in advance will give you a great deal of peace of mind.
If you experience side effects such as a headache or hot flashes after taking the drug, you can immediately consult with us and we will suggest countermeasures such as reducing the dose, changing the timing of taking the drug, and changing the content of your meal at the time of taking the drug. There are benefits.
Pharmacy/Drugstore
Few people have asked “Are there any ED treatments?” At pharmacies and drug stores.
Viagra Cialis Levitra is recognized as a prescription drug in USA, but it is not available without the instructions of a doctor.
If you inquire at a pharmacy or drug store, you may be offered supplements containing ingredients that are considered to be energetic agents, or drinks that are effective for nutrition and tonicity.
All of them are not ED treatments but supplements, so it seems that there are few that can be expected to have immediate effects.
The supplements sold at drug stores are dietary supplements that contain “maca”, “suppon extract”, “ginseng”, etc. that everyone has heard, so in the long run, I continued to take them. It is necessary to determine the effect on the above.
There are many situations in which ED treatments require the judgment of a doctor, such as side effects such as headache and red tide, and cardiovascular disease and hypertension cannot be used safely. It is no longer available.
This does not apply to pharmacies that operate online (major chain dispensing pharmacies and pharmacies that are not drug stores).
Beware of fake ED drugs
Especially when using an overseas personal import agency site, you need to be careful of counterfeits.
Even if it looks the same blue rhombus as Viagra and is the same size, there is a big difference in effectiveness and safety.
From those who used the personal import agency site, “Manufactured in a dirty place with poor quality control” “Since it does not work, when I analyzed the ingredients, it contained a lot of impurities and the active ingredient content was low” “Individual You may hear troubles such as “I couldn’t get in touch when I made a transfer to an import agency” or “Personal information was leaked”.
Instead of living a comfortable sexual life, you need to be careful because you may suffer health problems.
If you look at the fake and the real one side by side, it is easy to find the difference that the manufacturer’s “Pfizer” stamp is different, the size is slightly different, and the letters on the tablet sheet are different, but if you look only at the fake It’s hard to understand, so buy carefully.
We recommend that you be careful when purchasing when you see sales complaints on the Internet such as “great effect, bargain, foreign-made generic drug “.
It can be said to be one of the useful acquisition routes for those who want to reduce medical expenses and those who cannot go to a medical institution .
Beware of counterfeits of ED medicines ~How to distinguish genuine products~ Malicious counterfeits of ED medicines account for half of the products on the market, and they can even be found in hospitals. In order to protect yourself and improve ED, before you drink, choose a good hospital or genuine product guarantee site and check the shape and dosage before purchasing.
ED treatment drug summary
There are many types of ED drugs on the market, and it is no longer necessary to give up because you are not young anymore like you used to.
If you acquire the correct knowledge, follow the dosage and take it correctly, you can lead a safe and comfortable sexual life.
However, due to the expiration of patents for the original products and the spread of the Internet, the types of medicines available are increasing dramatically.
While it is possible to find products and doses that suit one’s own body and lifestyle, it is not uncommon for people to ignore contraindications and force themselves to purchase medicines or take counterfeit medicines, resulting in health hazards. .
In order to achieve a satisfying sex life, let’s choose a treatment method and ED drug with the correct knowledge.